Systemic lupus and kidney

As occurs in other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. In the United States, the annual incidence of systemic lupus erythematosus (SLE) averages 5.1 per 100,000 per year. Both discoid and systemic lupus are more common in women than men (about eight times more common). Signs and symptoms of kidney problems may include generalized itching, chest pain, nausea, vomiting and leg swelling (edema).
Pregnancy does not appear to worsen the long-term outcome of patients with lupus. Scientists suspect that neonatal lupus is caused in part by autoantibodies in the mother’s blood called anti-Ro (SSA) and anti-La (SSB). Many risk factors attribute to the development of lupus. Some people will have only a few symptoms, others may have them all.